Table 2:
Allele | Genotype | P value | Allele | P value | |||
---|---|---|---|---|---|---|---|
GG | GA | AA | G | A | |||
Obesity status | |||||||
Non-obese | 111 (68.1) | 48 (29.4) | 4 (2.5) | 0.862a | 270 (82.8) | 56 (17.2) | 0.913 |
Obese | 92 (67.2) | 42 (30.7) | 3 (2.2) | 227 (82.8) | 47 (17.2) | ||
Ethnicity | |||||||
Malay/Peninsular Bumiputera | 71 (72.4) | 26 (26.5) | 1 (1.1) | 0.030a | 158 (84.9) | 28 (15.1) | 0.019 |
Chinese | 85 (60.3) | 50 (35.5) | 6 (4.3) | 220 (78.0) | 62 (22.0) | ||
Indian | 47 (77.0) | 14 (23.0) | 0 (0.0) | 108 (88.5) | 14 (11.5) | ||
Gender | |||||||
Male | 77 (67.0) | 36 (31.3) | 2 (1.7) | 0.836a | 190 (82.6) | 40 (17.4) | 0.976 |
Female | 126 (68.1) | 54 (29.2) | 5 (2.7) | 306 (82.7) | 64 (17.3) | ||
Measurements | |||||||
SBP (mmHg)b | 138.33 (21.43) | 140.43 (22.11) | 135.00 (20.07) | 0.731 | 138.71 (21.52) | 139.70 (21.75) | 0.602 |
DBP (mmHg)c | 80.81 (11.13) | 82.98 (10.26) | 74.86 (8.90) | 0.504 | 81.20 (10.98) | 81.88 (10.39) | 0.642 |
Pulse rate (mmHg)b | 73.51 (14.58) | 73.09 (13.38) | 74.71 (14.51) | 0.923 | 73.44 (14.34) | 73.31 (13.40) | 0.905 |
WC (cm)b | 90.41 (11.34) | 91.05 (11.18) | 86.10 (12.79) | 0.469 | 90.52 (11.29) | 90.38 (11.40) | 0.876 |
WHRc | 0.89 (0.08) | 0.90 (0.09) | 0.87 (0.08) | 0.640 | 0.89 (0.08) | 0.89 (0.09) | 0.128 |
Height (cm)b | 159.50 (8.91) | 158.23 (18.02) | 156.64 (12.10) | 0.590 | 159.27 (11.11) | 158.01 (17.26) | 0.755 |
Weight (cm)b | 72.51 (58.81) | 69.35 (13.43) | 66.47 (15.68) | 0.716 | 71.94 (53.44) | 68.96 (13.62) | 0.744 |
BMI (kg/m2)b | 26.90 (5.06) | 27.17 (4.91) | 27.04 (5.35) | 0.945 | 26.95 (5.02) | 27.15 (4.91) | 0.756 |
TBF (%)b | 33.44 (7.08) | 33.44 (6.72) | 33.29 (6.86) | 0.961 | 33.44 (7.00) | 33.32 (6.67) | 0.824 |
SF (%)b | 27.34 (8.30) | 27.23 (8.18) | 28.27 (9.07) | 0.949 | 27.32 (8.27) | 27.37 (8.22) | 0.891 |
VFL (%)b | 11.82 (6.15) | 12.52 (6.22) | 11.71 (6.75) | 0.603 | 11.95 (6.15) | 12.41 (6.23) | 0.418 |
RM (kcal)b | 1431.58 (255.53) | 1451.04 (243.07) | 1392.43 (287.82) | 0.596 | 1435.11 (252.93) | 1443.15 (247.20) | 0.653 |
SM (%)b | 24.91 (4.17) | 24.82 (3.90) | 24.80 (4.42) | 0.993 | 24.90 (4.11) | 24.82 (3.93) | 0.973 |
Values for obesity status, ethnicity, and gender are in number of subjects (percentage). P values were determined by Pearson’s chi-square test, significant at P < 0.05. a Pearson’s chi-square test was performed for wild-type and combined mutant genotypes (GG and GA+AA) as some AA frequencies had values of less than 5.
Values for measurements are in mean (SD). P values were determined by b Mann–Whitney U or Kruskal–Wallis tests for nonnormally distributed data and c Student’s t test or ANOVA for normally distributed data, significant at P < 0.05.
Abbreviations: SBP = systolic blood pressure, DBP = diastolic blood pressure, WC = waist circumference, WHR = waist-to-hip ratio, BMI = body mass index, TBF = total body fat, SF = subcutaneous fat, VFL = visceral fat level, RM = resting metabolism, SM = skeletal muscle.