TABLE 2.

Comparison of the characteristics of the top-ranked tunnel clusters identified in MD simulations of LinB WT and LinB L177W using the CAVER 3.0 program

Tunnel cluster	Percentage of snapshots with identified tunnela		Average bottleneck radiusb		Maximum bottleneck radiusa
	LinB WT	LinB L177W	LinB WT	LinB L177W	LinB WT	LinB L177W
	%		Å		Å
p1b	73	44	1.1	1.0	1.9	1.7
p1a	48		1.0		1.8
p1 (p1b+p1a)	80	44	1.1	1.0	1.9	1.7
p2	18	17	0.9	0.9	1.6	1.5

^a Data were calculated with a probe radius of 1.0 Å.

^b Data were calculated with a probe radius of 0.7 Å.