Table 2.

Steps of asthma maintenance therapy during pregnancy

Step	Preferred controller medication	Alternative controller medication
1	none	-
2	Low-dose inhaled corticosteroid	LTRA, cromolyn, theophylline
3	Medium-dose inhaled corticosteroid	Low-dose inhaled corticosteroid + LABA or LTRA or theophylline
4	Medium-dose inhaled corticosteroid + LABA	Low-dose inhaled corticosteroid + LTRA or theophylline
5	High-dose inhaled corticosteroid + LABA	-
6	High-dose inhaled corticosteroid + LABA + oral corticosteroid	-

Definition of abbreviations: LTRA, leukotriene-receptor antagonist; LABA, long-acting beta-agonist. From [25] with permission.