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. 2012 Jul 31;44(1):25. doi: 10.1186/1297-9686-44-25

Table 3.

Accuracy of imputation for genotyping scenarios when removing subsets of individuals from the “Other” category

Scenario
Genotyping strategy1
2Imputation accuracy: R-squared
 
3Other
Grandparents
Parents
Testing individuals
 
 
MGS + PGS
MGD + PGD
Sire
Dam
 
 
 
 
  n2436 n = 63 n = 86 n = 41 n = 73 n = 98 L6k L3k L384
s4_100%
100 % H
H
L
H
L
L
.991
.985
.935
s4_50%
50 % H
H
L
H
L
L
.991
.984
.927
s4_25%
25 % H
H
L
H
L
L
.988
.981
.915
s5_100%
100 % H
H
0
H
0
L
.981
.968
.888
s5_50%
50 % H
H
0
H
0
L
.981
.968
.877
s5_25%
25 % H
H
0
H
0
L
.979
.966
.871
s12_100%
100 % H
0
0
0
0
L
.953
.931
.817
s12_50%
50 % H
0
0
0
0
L
.941
.914
.778
s12_25% 25 % H 0 0 0 0 L .917 .879 .759

1Animals were split into groups (ordered by generation) of testing individuals, their parents, and their grandparents; grandparents were further divided into two groups: MGS + PGS which included maternal grandsire and paternal grandsire, and MGD + PGD which included maternal granddam and paternal granddam; the remaining individuals were placed in the “Other” category; groups of animals were either genotyped at high density (H), low density (L) or not genotyped (0); 2Imputation accuracy (R-squared) for scenarios using SNP panels L6k, L3k and L384 on animals genotyped at low density; 3100 % H means that all of the individuals in the “Other” category are genotyped at high density, 50 % H means that only a random 50 % of the individuals in the “Other” category are genotyped at high density, 25 % H means that only a random 25 % of the individuals in the “Other” category are genotyped at high density.