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. 2012 Sep 3;28(18):i549–i555. doi: 10.1093/bioinformatics/bts384

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© The Author(s) (2012). Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. 6. — A Based on the statistics of binarized Transmission electron microscopy (TEM) images from (Hiroi et al., 2011) B realistically looking intracellular obstacle geometries were generated (Hiroi et al., 2012). C shows a 3D section of a generated volume, which looks similar like other 3D observations of membrane enclosed compartments like e.g. ER or Golgi (rendered with BioInspire from ScienceVisuals). D Diffusion through such a structured volume, simulated on the Gillespie level. Apparently at x = 3μm a high obstacle density leads to a lower particle density