Figure 3.

The relationship between false-positive information content and the number of sequences. The figure shows the theoretical upper bound on the information content threshold, D*, when one or more false-positive motif is expected to be observed in a dataset as function of the number of sequences, n (dashed line) compared to the strength of false-positive motifs detected by MEME (crosses). For both cases n is chosen from n = {10,20,30,50,100} and the parameters L = 1000 and W = 10 are fixed. The strength of motifs detected by MEME is consistent with the strength of motifs predicted to occur by chance for the given sample size.