Table 2. Combinations of smear microscopy, reference standard and MTB/RIF results within eligible patients.
Number of patients (%)* | Reference standard | Index test(MTB/RIF) | Smearmicroscopy | Comment | |
Löwenstein- Jensen | MGIT | ||||
30 (22.4) | + | + | + | + | full agreement |
13 (9.7) | + | + | + | – | false negative smear |
1 (0.7) | + | + | – | – | false negative MTB/RIF and smear |
1 (0.7) | – | – | + | + | false positive MTB/RIF and smear |
2 (1.5) | – | – | – | + | false positive smear |
1 (0.7) | – | – | + | – | false positive MTB/RIF |
1 (0.7) | – | + | + | + | false negative LJ |
82 (61.2) | – | – | – | – | full agreement |
1 (0.7) | contaminated | contaminated | – | – | contaminated reference standard |
2 (1.5) | – | – | invalid | – | invalid MTB/RIF |
Löwenstein-Jensen = LJ; MGIT = Mycobacteria Growth Indicator Tube; MTB/RIF = Xpert®MTB/RIF;
<$>\raster="rg2"<$> = positive result; <$>\raster="rg3"<$> = negative result; LJ and MGIT: composite reference standard.
Two eligible patients were excluded because they did not provide a second sputum sample.