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. Author manuscript; available in PMC: 2012 Oct 1.
Published in final edited form as: Invest Radiol. 2012 Oct;47(10):588–595. doi: 10.1097/RLI.0b013e318260abb3

TABLE 1.

Experimental design.

Capnic Condition
Normocapnia Hypocapnia Hypercapnia
Adjustable ventilator parameters
Breaths per minute 15–18 25–40 6–10
Tidal volume [ml] 250–300 275–340 110–175
Ratio of O2 and atmospheric air 0.3–0.4 0.2–0.4 0.5–1.0
Measured physiological parameters
Arterial pCO2 [kPa] 6.5 (5.6–7.6) 3.4 (2.5–4.4) 16.8 (12.1–22.0)
Heart rate [bmp] 82 (60–131) 89 (85–160) 186 (64–213)
Blood pressure 143/103 116/95 168/92
Systolic/diastolic [mmHg] (125–169/82–152) (72–152/62–121) (80–207/43–117)
pH 7.42 (7.32–7.49) 7.51 (7.29–7.60) 7.11 (6.86–7.87)
HA flow [l blood/min] 0.20 (0.03–0.53) 0.15 (0.07–0.29) 0.21 (0.03–0.70)
PV flow [l blood/min] 0.55 (0.40–1.20) 0.51 (0.28–0.91) 0.90 (0.36–1.84)
HA + PV flow [l blood/min] 0.70 (0.44–1.73) 0.69 (0.43–1.16) 1.28 (0.48–2.05)
HA/(HA+PV) 0.3 (0.1–0.4) 0.2 (0.1–0.7) 0.2 (0.1–0.4)

Values are shown as range or median (range) from studies in 10 pigs; pCO2, partial carbon dioxide tension in arterial blood; HA, hepatic artery; PV, portal vein.