Figure 1. In vivo growth of SKOV-3 tumor cells in SCID mice.
(A) In vivo growth of SKOV-3 C5a and controls revealed a significant reduction in tumor growth of SKOV-3 C5a. Following s.c. injection of SCID mice with SKOV-3 tumor cell lines (n=20, 16, 8 for SKOV-3 C5a, CV, WT; respectively), tumor growth was monitored by measuring two perpendicular diameters every 2–4 days. *p<0.05, **p<0.01, ***p<0.001. (B) Tumor weight measurement when all animals were sacrificed. **p<0.01, ***p<0.001.