Fig. 6. Effect of binge ethanol treatment on liver autophagy parameters.
CYP2E1 KI (A, C, D) or KO (B) mice were treated with ethanol in the absence of presence of 3MA or rapamycin. LC3I, II levels in KI (A) or KO mice (B); Levels of Akt or mTOR (C, D). *, P<0.05 compared with saline; **, P<0.05 compared with 3MA alone; #, P<0.05 compared with Rap alone. N=3.