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. Author manuscript; available in PMC: 2013 Sep 15.
Published in final edited form as: J Immunol. 2012 Aug 15;189(6):2727–2734. doi: 10.4049/jimmunol.1200380

Figure 7. 3BP2 silencing impairs FcεRI mediated degranulation in huMCs.

Figure 7

Biotinylated-IgE-sensitized CD34+ peripheral blood-derived huMCs with normal or reduced levels of 3BP2 (shRNA silenced) were stimulated with 100 ng/ml SA for 30 min. β-hexosaminidase release was measured in collected supernatants. Results are expressed as a percent of total β-hexosaminidase content reported as mean +/− SE. Data represent the mean of 3 independent experiments. Statistical significance (***p< 0.0001) is relative to NT shRNA.