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. 2012 Nov 15;17(10):1407–1416. doi: 10.1089/ars.2011.4377

FIG. 1.

FIG. 1.

TrxR1 activities in mtCCs after AFN, DNCB, or SFN treatment for 1 h. (A) AFN treatment decreased TrxR1 activity by approximately 90%; (B) DNCB treatment decreased TrxR1 activity by 62%; and (C) SFN treatment decreased TrxR1 activity by 21% compared with vehicle-treated controls. Data (mean±SEM, n=3–4) were analyzed by one-way ANOVA or unpaired t-test with significance noted at p<0.05 (*different than vehicle control). AFN, auranofin; ANOVA, analysis of variance; DNCB, dinitrochlorobenzene; mtCC, murine transformed Clara cells; SEM, standard error of the mean; SFN, sulforaphane; TrxR1, thioredoxin reductase-1.