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. 2000 Jun 20;97(13):6974–6980. doi: 10.1073/pnas.97.13.6974

Table 3.

The distribution of nonsilent (NS) substitutions across internal and terminal branches

Branch type Number of branches Exp NS Obs NS χ2
Terminal 357 373.6 510 49.8
Internal 355 371.4 235 50.1
Sum 712 745.0 745 99.9

The tree in Fig. 1 has significantly more nonsilent substitutions assigned to its terminal branches than expected based on the relative numbers of internal and terminal branches (P < 0.05, df = 1). Exp, expected; Obs, observed.