Table 2.
Comparison of all collected data between neonates with and without sepsis (univariate analysis)
| Variable |
With sepsis |
Without sepsis |
P |
|---|---|---|---|
| N = 514 (%) | N = 11276 (%) | ||
|
Neonate-related | |||
| Gender (feminine/masculine) |
233/281 |
5542/5732 |
0.22 |
| Gestational age (wk)* |
34 ± 4.3 |
39 ± 2.3 |
<0.0001 |
| Birth weight (g)* |
2069 ± 837 |
3053 ± 576 |
<0.0001 |
| Height (cm)* |
43.4 ± 5.9 |
49.3 ± 3.3 |
<0.0001 |
| Premature (≤37 wks) |
350 (68.1) |
1581 (14.0) |
<0.0001 |
| Postmature (≥42 wks) |
5 (1.0) |
131 (1.2) |
0.45 |
| Product of multiple pregnancy |
41 (8.0) |
204 (1.8) |
<0.0001 |
| Abnormal umbilical cord |
131 (25.5) |
1620 (14.4) |
<0.0001 |
| With perinatal asphyxia |
17 (3.3) |
81 (0.7) |
<0.0001 |
| With intrauterine hypoxia |
10 (1.9) |
71 (0.6) |
0.003 |
| Apgar score ≤5 |
274 (53.3) |
1,765 (15.7) |
<0.0001 |
| With fetal distress |
86 (16.7) |
896 (7.9) |
<0.0001 |
|
Maternal-related | |||
| Age (yrs)* |
26 ± 5.5 |
25 ± 5.4 |
0.10 |
| Low educative level |
284 (55.3) |
6341 (56.2) |
0.341 |
| Gestations* |
2 ± 1.2 |
2 ± 1.1 |
0.01 |
| Deliveries* |
0.5 ± 0.9 |
0.6 ± 0.9 |
0.001 |
| Non-adequate pregnancy control |
258 (50.2) |
4112 (36.5) |
<0.0001 |
| Experienced threat of abortion during this pregnancy |
139 (27.0) |
1905 (16.9) |
<0.0001 |
| Abnormal placenta |
86 (16.7) |
436 (3.9) |
<0.0001 |
| Dystocic delivery |
151 (24.9) |
5900 (52.3) |
<0.0001 |
| Cesarean section |
359 (69.8) |
5232 (46.4) |
<0.0001 |
| Abnormal amniotic fluid |
159 (30.9) |
1687 (15.0) |
<0.0001 |
| Premature membrane rapture > 12 h |
168 (32.7) |
469 (4.2) |
<0.0001 |
| Premature membrane rapture > 24 h |
137 (26.7) |
222 (2.0) |
<0.0001 |
| Premature membrane rapture > 48 h |
85 (26.7) |
105 (0.9) |
<0.0001 |
| Amnionitis |
4 (0.8) |
32 (0.3) |
0.074 |
| Preeclampsia ≤35 gestational wks |
28 (5.4) |
340 (3.0) |
<0.0001 |
| Preeclampsia >35 gestational wks |
26 (5.1) |
569 (5.0) |
0.530 |
| Metabolic disease ≤35 gestational wks |
27 (5.3) |
326 (2.9) |
0.002 |
| Metabolic disease >35 gestational wks |
26 (5.1) |
343 (3.0) |
0.007 |
| Infectious disease ≤35 gestational wks |
164 (31.9) |
2793 (24.8) |
<0.0001 |
| Infectious disease >35 gestational wks |
79 (15.4) |
1270 (11.3) |
0.003 |
|
Clinical-course and medical-care related | |||
| Reanimation required |
339 (66.0) |
3888 (34.5) |
<0.0001 |
| Mechanical ventilation required |
160 (31.1) |
209 (1.9) |
<0.0001 |
| O2 inspiration fraction required > 60 % |
95 (18.5) |
96 (0.9) |
<0.0001 |
| Continuous positive airway pressure required |
24 (4.7) |
14 (0.01) |
<0.0001 |
| Surfactant administration |
49 (9.5) |
34 (0.3) |
<0.0001 |
| Respiratory complication |
35 (6.8) |
91 (0.8) |
<0.0001 |
| Intraventricular bleeding |
20 (3.9) |
28 (0.2) |
<0.0001 |
| Surgical procedure required |
14 (2.7) |
10 (0.1) |
<0.0001 |
| Medical procedure required | 293 (57.0) | 609 (5.4) | <0.0001 |
*Mean ± Standard deviation (SD).