Table 4.
Comparison of all collected data between deceased and surviving septic neonates (univariate analysis)
| Variable |
Deceased |
Surviving |
P |
|---|---|---|---|
| N = 49 (%) | N = 465 (%) | ||
|
Neonate-related | |||
| Gender (feminine/masculine) |
21/28 |
212/253 |
0.41 |
| Gestational age (wk)* |
31.3 ± 5.2 |
34.0 ± 4.1 |
<0.0001 |
| Birth weight (g)* |
1486 ± 867 |
2130 ± 852 |
<0.0001 |
| Height (cm)* |
38.2 ± 6.2 |
44.0 ± 5.6 |
<0.0001 |
| Premature (≤37 wks) |
38 (77.5) |
153 (32.2) |
0.08 |
| Postmature (≥42 wks) |
1 (2.0) |
4 (0.9) |
0.39 |
| Product of multiple pregnancy |
7 (14.3) |
34 (7.3) |
0.08 |
| Abnormal umbilical cord |
14 (28.6) |
117 (25.2) |
0.35 |
| With perinatal asphyxia |
9 (18.4) |
8 (1.7) |
<0.0001 |
| With intrauterine hypoxia |
3 (6.1) |
7 (1.5) |
0.06 |
| Apgar score ≤5 |
42 (85.7) |
232 (49.9) |
<0.0001 |
| With fetal distress |
13 (26.5) |
73 (15.7) |
0.04 |
|
Maternal-related | |||
| Age (yrs)* |
27.0 ± 5.8 |
26.3 ± 5.5 |
0.42 |
| Low educative level |
26 (53.1) |
258 (55.5) |
0.43 |
| Gestations* |
2.3 ± 1.3 |
1.9 ± 1.2 |
0.06 |
| Abortions* |
0.4 ± 0.7 |
0.2 ± 0.5 |
0.01 |
| Non-adequate pregnancy control |
30 (61.2) |
228 (49.0) |
0.07 |
| With threat of abortion during this pregnancy |
19 (38.8) |
120 (25.8) |
0.04 |
| Abnormal placenta |
15 (30.6) |
71 (15.3) |
0.008 |
| Abnormal amniotic fluid |
20 (40.8) |
139 (29.9) |
0.08 |
| Dystocic delivery |
16 (32.7) |
135 (29.0) |
0.35 |
| Cesarean section |
32 (65.3) |
327 (70.3) |
0.28 |
| Premature membrane rupture >12 h |
10 (20.4) |
158 (34.0) |
0.03 |
| Premature membrane rupture >48 h |
7 (14.3) |
130 (28.0) |
0.02 |
| Premature membrane rupture >24 h |
5 (10.2) |
80 (17.2) |
0.14 |
| Amnionitis |
0 |
4 (0.9) |
0.66 |
| Preeclampsia ≤35 gestational wks |
3 (6.1) |
25 (5.4) |
0.51 |
| Preeclampsia >35 gestational wks |
2 (4.1) |
24 (5.2) |
0.54 |
| Metabolic disease ≤35 gestational wks |
4 (8.2) |
23 (4.9) |
0.25 |
| Metabolic disease >35 gestational wks |
1 (2.0) |
25 (5.4) |
0.26 |
| Infectious disease ≤35 gestational wks |
17 (34.7) |
147 (31.6) |
0.38 |
| Infectious disease >35 gestational wks |
7 (14.3) |
72 (15.5) |
0.51 |
|
Clinical course- and medical care-related | |||
| Reanimation required |
45 (91.8) |
294 (63.2) |
<0.0001 |
| Mechanical ventilation required |
37 (75.5) |
123 (26.5) |
<0.0001 |
| O2 inspiration fraction >60 % required |
23 (46.9) |
72 (15.5) |
<0.0001 |
| Continuous positive airway pressure required |
6 (12.2) |
18 (3.9) |
0.02 |
| Surfactant administration |
16 (32.7) |
33 (7.1) |
<0.0001 |
| Respiratory complication |
1 (2.0) |
34 (7.3) |
0.13 |
| Intraventricular bleeding |
9 (18.4) |
11 (2.4) |
<0.0001 |
| Surgical procedure required |
4 (8.2) |
19 (2.2) |
0.03 |
| Invasive medical procedure required | 48 (97.8) | 245 (52.5) | <0.0001 |
*Mean ± Standard deviation (SD).