Fig. 5.

Effect of VPA on the cell cycle in the process of liver regeneration

N=3 for each. (a) Expressions of cell cyclin proteins in the two groups of PH and VPA+PH at sequential time points were detected by Western blot with antibody cyclin D1, cyclin E, CDK4 and CDK2 at 0, 12, 24, 36, 48, 72, 120, or 168 h in the PH and VPA+PH groups. (b) Corresponding densitometric analyses of immunodetection of certain antibodies. GAPDH was performed as a loading control. ^* P<0.05, ^** P<0.01, ^*** P<0.001 when the VPA(PH group is compared with the PH group at the same time point