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Diagram of the extent of gRNA-mediated editing of maxicircle cryptogenes in the old laboratory UC strain of L. tarentolae and the recently isolated LEM125 strain. The overlapping gRNAs that give rise to the overall 3′ to 5′ editing within a domain are indicated. In the LEM125 strain, all of the approximately 80 predicted gRNAs are indicated although only 47 gRNAs have been identified.
