Table 7. SST results of 149 pauci-cellular samples.
| Suspected lymphoma localized in CSF (n=115) | |
|---|---|
| Aberrant/clonal B-cell populationsa (1 CLL, 1 BL, 1 FL, 1 MCL, 2 DLBCL, 1 B-cell lymphoma, 2 unknown) | 9/115 (7.8%) |
| Aberrant T-cell populations (T-cell lymphoma, PTLD) | 2/115 (1.7%) |
| Suspicious of other hematological malignancies in CSF (n=11) | |
| Aberrant plasma cell populations | 2/11 (18.1%) |
| Vitreous biopsy (n=23) | |
| Aberrant/clonal B-cell populations |
2/23 (8.7%) |
| Total | 15/149b (10.0%) |
Abbreviations: BL, Burkitt lymphoma; CNS, central nervous system; CLL, chronic lymphocytic leukemia; CSF, cerebrospinal fluid; DLBCL, diffuse large B-cell lymphoma; FL, follicular lymphoma; FNA, fine needle aspirate; IOL, intraocular lymphoma; PTLD, post-transplant lymphoproliferative disease; SST, small sample tube.
a
In one case a parallel FNA brain biopsy was analyzed next to the CSF sample, showing the same aberrant B-cell population;
b
All positive cases had a final diagnosis of CNS lymphoma or IOL based on histopathological analysis, imaging techniques and/or the clinical behavior of the disease, while none of the negative cases by the SST labeling was diagnosed as having CNS or IOL.