Figure 5.

Effect of albitiazolium on choline transport in P. falciparum-infected erythrocytes. (A) Inhibition of 15 µM choline entry into P. falciparum-infected erythrocytes by albitiazolium (albi) was determined after 10 min of incubation in presence or not of 150 µM furosemide. (B) The initial velocities of choline uptake into P. falciparum IRBC in the presence of increasing concentrations of albitiazolium are shown as Lineweaver–Burk double-reciprocal plots. Inhibitor concentrations were 0, 4, 6 and 10 µM albitiazolium. Experiments were repeated twice.