Table 2.
Polymorphisms in 10 loci of P. falciparum
| Gene | Chromosome location | Length, bp | Sequences in the sample, ni | Nonsynonymous polymorphisms, Dn | Synonymous polymorphisms, Ds | Synonymous sites analyzed
|
|
|---|---|---|---|---|---|---|---|
| 4-fold, nili | 2-fold, nimi | ||||||
| Dhfr | 4 | 609 | 32 | 4 | 0 | 2,144 | 4,128 |
| Ts | 4 | 1,215 | 10 | 0 | 0 | 1,250 | 2,640 |
| Dhps | 8 | 1,269 | 12 | 5 | 0 | 1,536 | 2,724 |
| Mdr1 | 5 | 4,758 | 3 | 1 | 0 | 1,350 | 2,088 |
| Rap1 | — | 2,349 | 9 | 8 | 0 | 1,092 | 1,668 |
| Calm | 14 | 441 | 7 | 0 | 0 | 364 | 602 |
| G6pd | 14 | 2,205 | 3 | 9 | 0 | 726 | 1,404 |
| Hsp86 | 7 | 2,241 | 2 | 0 | 0 | 532 | 910 |
| Tpi | — | 597 | 2 | 0 | 0 | 180 | 262 |
| Csp 5′end | 3 | 387 | 25 | 7 | 0 | 688 | 2,010 |
| Csp 3′end | 3 | 378 | 25 | 17 | 0 | 1,050 | 1,625 |
| Total | — | — | — | 51 | 0 | 10,912 | 20,061 |
Modified from ref. 12.