Table 2.
Cycle | N | CR Adjusted rate (95% CI) | Emesis-free Adjusted rate (95% CI) | CC Adjusted rate (95% CI) |
---|---|---|---|---|
1 | 156 | 0.744 (0.675, 0.812) | 0.923 (0.882, 0.964) | 0.744 (0.675, 0.812) |
2 | 156 | 0.776 (0.710, 0.841) | 0.929 (0.890, 0.969) | 0.776 (0.710, 0.841) |
3 | 156 | 0.795 (0.731, 0.858) | 0.936 (0.898, 0.974) | 0.795 (0.731, 0.858) |
4 | 153 | 0.786 (0.721, 0.851) | 0.922 (0.881, 0.964) | 0.786 (0.721, 0.851) |
5 | 120 | 0.811 (0.744, 0.879) | 0.906 (0.858, 0.954) | 0.811 (0.744, 0.879) |
6 | 118 | 0.820 (0.753, 0.887) | 0.925 (0.881, 0.970) | 0.820 (0.753, 0.887) |
CI, confidence interval; CR, complete response: no vomiting and no use of rescue medication; emesis-free, no emetic episodes; CC, complete control: no vomiting, no rescue medication and no more than mild nausea.