Table 1.
Characteristic | n (%) unless otherwise indicated |
---|---|
Age | 56.40 (9.43)* |
Male sex | 43 (78.18) |
Race | |
African American | 21 (38.18) |
White | 26 (47.27) |
Other$ | 8 (14.55) |
Cause of cirrhosis | |
Hepatitis C | 16 (29.09) |
Alcohol | 14 (25.45) |
Hepatitis C and alcohol | 10 (18.18) |
Hepatitis B | 3 (5.45) |
Nonalcoholic steatohepatitis | 3 (5.45) |
Cryptogenic cirrhosis | 3 (5.45) |
Other# | 6 (10.90) |
MELD score | 23.80 (8.43)* |
Serum creatinine | 1.70 (1.20, 2.60)‡ |
Serum bilirubin | 5.40 (2.10, 11.60)‡ |
Serum INR | 1.60 (1.40, 2.10)‡ |
Serum sodium | 133.09 (7.43)* |
Immunocompromised status | 6 (10.91) |
Variceal hemorrhage | 8 (14.55) |
On antibiotics at time of diagnosis¶ | 5 (9.09) |
Gram-stain positive | 6 (13.95)§ |
Initial peritoneal fluid PMN cell count | 773.10 (517.50, 2188.80)‡ |
Repeat peritoneal fluid PMN cell count | 127.60 (56.60, 607.60)‡ |
Peritoneal fluid culture positive** | 22 (40.00) |
Gram positive | 8 (14.54) |
Gram negative | 11 (20.00) |
INR, international normalized ratio; MELD, model for end-stage liver disease; PMN, polymorphonyclear.
Mean (SD).
Other races: Hispanic (6), Middle Eastern (1), Eygptian (1).
Other causes of ascites: cirrhosis from alpha-1-antitrypsin deficiency (2), autoimmune hepatitis (2), giant-cell hepatitis (1), biliary obstruction (1).
Median (Q1, Q3).
Antibiotic regimens: ciprofloxacin weekly for prophylaxis of spontaneous bacterial peritonitis (SBP) (1), ciprofloxacin weekly for SBP prophylaxis and metronidazole for extraperitoneal infection (1), trimethoprim and sulfamethoxazole prophylaxis for patient with HIV (1). Other antibiotic regimens for extraperitoneal infections included dapsone/trimethoprim and sulfamethoxazole/ampicillin (1), vancomycin/cefepime (1).
Gram stain not performed on 12 (21.81) patients.
Peritoneal fluid culture was negative in 31 (56.36%) patients and not performed on 2 (3.63%) patients. Fluid culture was multi-organismal in 3 (5.45%) patients.