Table 2.
Priority cancer chemopreventive agents
| Class of agent | Chemical/brand name | Preventive targets |
|---|---|---|
| Selective estrogen receptor modulators and other hormonal agents |
Tamoxifen |
Breast |
| Arzoxifene |
Breast |
|
| Acolbifene |
Breast |
|
| Raxoxifene/Evista® |
Breast |
|
| Finasteride |
Prostate |
|
| Nonsteroidal anti- inflammatory drugs |
Celecoxib/Celebrex® |
Colon, breast, prostate, bladder |
| Sulindac/Clinoril® |
Esophagus, skin |
|
| Aspirin |
|
|
| Minerals and micronutrients |
Calcium compounds |
Colon |
| Glucocorticoids |
Budesonide |
Lung |
| Retinoids |
All-trans-retinoic acid tretinoin/Retin-A® |
Cervix, esophagus, larynx, lung, |
| |
9-cis-Retinoic acid alitretinoin/Panretin® |
Nasopharynx, oral cavity, ovary |
| |
13-cis-Retinoic acid isotreninoin/Accutane® |
|
| 4-Hydroxyretinamide, (4-HPR) fenretinide |