Table 5.
Risk of optic atrophy
| Study | Test intervention | No. with outcome/No. in group | Control intervention | No. with outcome | Total No./No. with outcome |
|---|---|---|---|---|---|
| Aminocaproic acid | |||||
| Crouch 1976 | Oral aminocaproic acid | 0/32 | Placebo | 2/27 | 2/59 |
| Crouch 1997 | Oral aminocaproic acid | 0/29 | Topical aminocaproic acid | 0/35 | 0/64 |
| Tranexamic acid | |||||
| Varnek 1980 | Tranexamic acid | 1/102 | Conservative treatment | 0/130 | 1/232 |
| Cortisone | |||||
| Zetterstrom 1969 | Atropine plus cortisone eye drops | 0/58 | Conservative treatment | 1/59 | 1/117 |
| Non-drug medical interventions | |||||
| Read 1974 | Bed rest with elevation of the head, bilateral patches and eye shield | NR | Moderate ambulatory activity, patching and shielding of injured eye | NR | 8/137 |
NR: Not reported