Table 2.
Region | Hemisphere | BA | X | Y | Z | Cluster(voxels) |
---|---|---|---|---|---|---|
Healthy > PO-MDD | ||||||
Middle Temporal Gyrus | R | 21 | 61 | −43 | −4 | 111 |
Inferior Parietal Lobule | R | 40 | 39 | −58 | 48 | 137 |
Cerebellum | R | 40 | −66 | −18 | 98 | |
PO-MDD > Healthy | ||||||
Middle Temporal Gyrusa | R | 21 | 46 | 3 | −18 | 130 |
Caudate/Subgenual Cingulateb |
R | 24 | 0 | 14 | −2 | 163 |
Middle Temporal Gyrus | L | 21 | −37 | 4 | −29 | 198 |
Anterior Cingulate Cortexc | L | 32 | −8 | 41 | 14 | 60 |
No longer significant after covarying for comorbidity (see text)
No longer significant after covarying for age and gender, comorbidity, or current depressive affect and impairment (see text)
Connectivity with posterior cingulate seed significantly related to emotion regulation and coping behavior (see text and Figure 2)