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. Author manuscript; available in PMC: 2012 Sep 10.
Published in final edited form as: Dev Dyn. 2010 Jan;239(1):77–93. doi: 10.1002/dvdy.22059

Figure 3.

Figure 3

Planar Cell Polarity in the Drosophila Wing. Drosophila wing hairs form in the apical distal region of wing cells. The asymmetric localization of planar cell polarity signaling components is important to establish this polarity. On the distal side of the cells, Diego (Dgo) promotes the activation of localized Dishevelled (Dsh) by coordinating its binding with Frizzled (Fz). The localization of the signaling inhibitors Strabismus (Stb) and Prickle (Pk) on the proximal side of the wing cell prevent activation of Dishevelled and growth of the wing hair on the proximal side.