Figure 2. The Four Molecules of Unliganded Kapβ2 in the Asymmetric Unit Show Conformational Heterogeneity.
(A) Four NCS-related Kapβ2s (chains A–D) are superimposed at H8–H13. The chains (each in a different shade of blue) are drawn as spheres at the geometric center of each HEAT repeat. Maximum deviations between geometric centers at the termini are shown. (B) Results of TLSMD analysis for partitioning of the four Kapβ2 chains into two to four TLS groups (each in a different color).