Skip to main content
. Author manuscript; available in PMC: 2012 Sep 10.
Published in final edited form as: Bioorg Med Chem Lett. 2008 Sep 26;18(21):5753–5757. doi: 10.1016/j.bmcl.2008.09.084

Fig 2.

Fig 2

Compound 11j inhibited S(−)-nicotine evoked [3H]DA overflow from rat striatal slices in concentration-dependent manner. Slices were superfused in the absence (control) or presence of analogue for 36 min prior to S(−)-nicotine addition to the buffer. Superfusion continued for 36 min with S(−)-nicotine added to the buffer. Control represents [3H]DA overflow in response to nicotine (10 µM). Data are expressed as mean ± SEM [3H]DA overflow. n = 4 rats/analogue.