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Axial PET (a), CT (b), and fused PET/CT (c) images obtained in a Biograph Duo LSO (Siemens) two hours after i.v. injection of 368 MBq of FMISO, in a 64-year-old woman with a left-sided triple negative infiltrating ductal carcinoma, T2N1M0. Peripheral tumour uptake of FMISO (SUVmax = 1,44) consistent with hypoxia (arrow), and inside tumour lack of activity due to central necrosis (∗) were observed. Physiological uptake in muscles and mediastinum was identified.
