Table 4.
PK parameters of compound 19.
| cmpd | oral dose (mg/kg) |
Cmax (nM) |
Tmax (min.) |
AUC (0-t) (nM·h) |
t1/2 (h) | F (%) |
|---|---|---|---|---|---|---|
| 19 | 20 | 162 ± 32 | 45 ± 21 | 305 ± 34 | 1.3 ± 0.64 | 35 |
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