Fig. 1.

Increased RIP3 and RIP1 expression in the late phase of retinal degeneration in rd10 mice. (A and B) Quantitative real-time PCR analysis for RIP3 (A) and RIP1 (B) in WT and rd10 retinas at P21 and P35 (n = 5–7 each). **P < 0.01. (C) Western blot analysis for RIP3 and RIP1 at P21 and P35 of WT and rd10 retinas (n = 4 each). Levels normalized to β-tubulin. For RIP3 analysis, spleen samples from WT and Rip3^−/− animals were used as positive and negative controls, respectively. The bar graphs indicate the relative level of RIP3 and RIP1 to β-tubulin by densitometric analysis. *P < 0.05.