Skip to main content
. 2004 Jan;24(2):487–501. doi: 10.1128/MCB.24.2.487-501.2004

FIG. 9.

FIG. 9.

The 13 unique residues together with the N-terminal PXXP motifs in ΔNp73 form a novel activation domain. (A) Schematic representation of structures of p73β, ΔNp73β, and various Gal4-p73 chimeric proteins. (B) The 13 unique residues together with the N-terminal PXXP motifs in ΔNp73 form an activation domain. Half a microgram of a control vector, pcDNA3.1, or of a vector expressing Gal4 and various Gal4-p73 chimeric proteins as listed on the left was cotransfected into H1299 cells with 0.25 μg of a luciferase reporter, pGL2-5Gal. The increase (n-fold) in relative luciferase activity is a product of the luciferase activity induced by Gal4 or various Gal4-p73 chimeric proteins divided by that induced by pcDNA3.1.