Table 5.
Distribution of CD4+ and CD8+ T-cell subsets among the Pediatric AIDS Clinical Trials Group protocol 366 (PACTG 366) participants included in the analysis.
| T-cell subset | Cell counts (cells/mm3)
|
Percentages
|
||||
|---|---|---|---|---|---|---|
| N | Mean (SD) | Median (range) | N | Mean (SD) | Median (range) | |
| CD4+CD38+HLADR− | 121 | 422 (444) | 251 (0–2061) | 124 | 64 (23) | 69 (1–95) |
| CD4+CD38+HLADR+ | 121 | 66 (83) | 43 (0–550) | 124 | 17 (18) | 13 (0–92) |
| CD4+CD38−HLADR− | 121 | 62 (64) | 46 (0–371) | 124 | 14 (11) | 11 (0–76) |
| CD4+CD38−HLADR+ | 121 | 17 (19) | 11 (0–126) | 124 | 5 (5) | 3 (0–34) |
| All CD4+CD38+ | 121 | 488 (470) | 343 (2–2248) | 124 | 82 (13) | 85 (23–98) |
| All CD4+HLADR+ | 121 | 82 (95) | 56 (0–580) | 124 | 22 (21) | 15 (0–97) |
| All CD4+ | 123 | 570 (499) | 423 (2–2342) | 123 | 20 (11) | 19 (1–59) |
| CD8+CD38+HLADR− | 122 | 447 (323) | 366 (0–1575) | 125 | 41 (17) | 39 (0–80) |
| CD8+CD38+HLADR+ | 122 | 497 (550) | 345 (0–3922) | 125 | 39 (20) | 38 (0–91) |
| CD8+CD38−HLADR− | 122 | 165 (189) | 103 (0–974) | 125 | 15 (14) | 10 (0–70) |
| CD8+CD38−HLADR+ | 122 | 80 (124) | 36 (0–736) | 125 | 6 (7) | 4 (0–38) |
| All CD8+CD38+ | 122 | 945 (688) | 865 (66–4510) | 125 | 80 (16) | 83 (29–102) |
| All CD8+HLADR+ | 122 | 577 (632) | 384 (0–4216) | 125 | 44 (22) | 46 (0–99) |
| All CD8+ | 123 | 1191 (811) | 1044 (80–4902) | 123 | 46 (14) | 44 (14–76) |
HLADR, human leukocyte antigen DR.