Table 3.

Haplotype frequencies and Odds ratio for gene IL-1RN and IL-1α

			Number of haplotype for		Crude OR	Adjusted OR*
SNP	Haplotype	p-value**	Asymptomatic Atherosclerosis	Symptomatic Atherosclerosis	Estimate	Estimate
IL-1RN	1212122	0.05	77	85	1.00
	1112222		22	14	0.58	0.59
	1211122	0.01	41	18	0.39	0.40
	2222111		69	57	0.74	0.72
IL-1α	111212212		82	79	1.00
	111211212	0.07	71	45	0.66	0.64
	222122121		54	51	0.98	0.94

^*Adjusted for all 9 variables in table 1

^**the haplotypes showing significant association (p<0.1) in stepwise regression (Zaykin 2002).