Table 4.

Diplotype (combination of haplotype pair) frequencies and Odds ratio for gene IL-1RN and IL-1α

	Number of subjects		Crude Odds Ratio			Adjusted Odds Ratio*
No. of the haplotype copies	Asymptomatic Atherosclerosis	Symptomatic Atherosclerosis	Estimate	95%CI	p-value	Estim ate	95%CI	p- value
IL-1α:111211212
0	41	49	1.0 (ref)			1.0 (ref)
1	52	30	0.48	0.26 - 0.89	0.0197	0.47	0.25 - 0.89	0.0213
2	9	7	0.65	0.23 - 1.85	0.4185	0.64	0.22 - 1.88	0.4171
1 or 2			0.51	0.28 - 0.91	0.0225	0.50	0.27 - 0.91	0.0241
IL-1RN: 1211122				-			-
0	64	68	1.0 (ref)	-		1.0 (ref)	-
1	37	15	0.39	0.2 - 0.77	0.0071	0.42	0.2 - 0.85	0.0169
2	2	1	0.48	0.05 - 4.82	0.5316	0.37	0.03 - 4.03	0.4167
1 or 2			0.39	0.2 - 0.77	0.0064	0.41	0.2 - 0.84	0.0139
IL-1RN: 1212122
0	40	24	1.0 (ref)			1.0 (ref)
1	52	42	1.36	0.71 - 2.61	0.3599	1.43	0.72 - 2.85	0.3050
2	12	19	2.80	1.15 - 6.8	0.0234	2.85	1.11 - 7.33	0.0292