Table 5.

Logistic analysis for two SNPs combined

Genotype		Number of subjects for		Crude OR		Adjusted OR*
SNP1 genotypes	SNP2 genotypes	Asymptomatic Atherosclerosis	Symptomatic Atherosclerosis	Estimate	p-value	Estimate	p-value
IL-1αrs2071373	IL-1RN rs315921
11 or 12	12 or 22	23	6	1.0 (ref)		1.0 (ref)
22 or 22	11	36	28	3.0	0.0366	2.7	0.0690
22	12 or 22	16	12	2.9	0.0767	2.9	0.0804
11	11	17	32	4.5	0.0041	4.1	0.0104
IL-1α rs2071373	IL-1RN rs315934
11 or 12	11 or 12	25	7	1.0 (ref)		1.0 (ref)
12 or 22	22	31	27	3.1	0.0238	2.7	0.0558
22	11 or 12	12	8	2.4	0.1654	2.2	0.2170
11	22	24	35	5.2	0.0010	4.7	0.0032
IL-1α rs2071373	IL-1RN rs315946
11 or 12	12 or 22	15	5	1.0 (ref)		1.0 (ref)
12 or 22	11	40	29	2.2	0.1736	2.1	0.2054
22	12 or 22	16	9	1.7	0.4304	1.8	0.4068
11	11	25	33	4.0	0.0177	3.9	0.0256

^*Adjusted for all 9 variables in table 1