Table 3.
Interaction of FKBP5 Diplotypes and Childhood Trauma on Violent Behavior While in Jaila
| CTQ | ||||||
|---|---|---|---|---|---|---|
| Variable | Emotional Abuse | Physical Abuse | Sexual Abuse | Emotional Neglect | Physical Neglect | Total |
| Abuse or neglect | ||||||
| LR χ2 | 1.9 | 13.4 | 0.1 | 5.4 | 6.5 | 6.6 |
| P value | .17 | .0003 | .75 | .02 | .01 | .01 |
| Age | ||||||
| LR χ2 | 5.7 | 10.7 | 4.8 | 10.1 | 4.7 | 6.5 |
| P value | .02 | .001 | .02 | .002 | .03 | .01 |
| Axis I diagnosis | ||||||
| LRχ2 | 5.1 | 1.2 | 3.2 | 3.0 | 3.7 | 7.5 |
| P value | .02 | .27 | .07 | .10 | .05 | .006 |
| Diplotype effect | ||||||
| LR χ2 | 0.9 | 3.2 | 2.5 | 0.4 | 0.4 | 0.3 |
| P value | .64 | .20 | .30 | .80 | .82 | .84 |
| Gene-environment | ||||||
| LR χ2 | 3.9 | 10.5 | 3.9 | 3.9 | 5.1 | 5.1 |
| P value | .14 | .005 (.025) | .14 | .13 | .07 | .07 |
| Whole model | ||||||
| LR χ2 | 20.2 | 31.3 | 21.5 | 24.3 | 21.2 | 28.0 |
| r2 | 0.08 | 0.11 | 0.08 | 0.08 | 0.06 | 0.06 |
| P value | .0051 | <.0001 | .003 | .001 | .0034 | .0002 |
Abbreviations: CTQ, Childhood Trauma Questionnaire; LR, likelihood ratio.
a
The values in parentheses represent P values after false discovery rate correction for multiple comparisons. There were 411 prisoners, of whom 185 do not have a history of childhood maltreatment: 91 experienced physical abuse, 58 sexual abuse, 67 emotional abuse, 91 emotional neglect, and 151 physical neglect. A total of 226 individuals experienced at least 1 form of abuse and/or neglect (CTQ total), and 181 had an Axis I diagnosis.