Table 3.
Association of SNPs with disease phenotype
| |
|
|
|
|
Significance of SNP distribution in Invasive amebic liver abscess, dysentery and Asymptomatic disease |
|
|---|---|---|---|---|---|---|
| Genbank#accession number | AmoebaDB ID | Non-synonomous substitution | Location in reference contig | SNP | p value | q-value |
|
XM_647889.1& |
EHI_080100 |
Pro361Leu |
2725C/T |
1 |
0.002** |
0.032** |
|
XM_647310.1& |
EHI_065250 |
Ser399Asp |
10296A/G |
3 |
0.05** |
0.3 |
| 10297G/A |
4 |
|
|
|||
|
XM_644633.2 |
EHI_200030 |
Leu60Ile |
16181C/A |
8 |
0.08 |
0.31 |
|
XM_646031.2 |
EHI_120270 |
Pro21Ser |
7994C/T |
9 |
0.10 |
0.31 |
|
XM_647889.1 |
EHI_008810 |
Leu326Ile |
73463C/A |
10 |
0.24 |
0.44 |
|
XM_643253.1 |
EHI_040810 |
Ala197Glu |
1216C/A |
11 |
0.31 |
0.46 |
|
XM_645270.1 |
EHI_105150 |
Ile282Met |
27395T/G |
12 |
0.42 |
0.56 |
|
XM_001913781.1 |
EHI_138990 |
Val1288Leu |
30231G/T |
13 |
0.52 |
0.64 |
|
XM_651449.1 |
EHI_042210 |
Pro58Leu |
39051C/T |
14 |
0.92 |
1.00 |
| XM_648423.2& | EHI_016380 | Tyr702His | 17795T/C | 15 | 0.97 | 1.00 |
#Only loci with diversity H value over 0.25 shown.
** <0.05.
&Representative SNP chosen in linked SNP data sets.