Table 3.
Characteristics of Circle participants with eGFR = > 60 by degree of albuminuria
| PARAMETER* | People With eGFR = > 60 and Urine Albumin (UA) Test | ||||
|---|---|---|---|---|---|
| |
Total With UA |
UA neg (non-CKD) |
Micro-albuminuria** |
Macro-albuminuria** |
p |
| NUMBER (%) |
583 (100) |
242 (41.5) |
247 (42.4) |
94 (16.1) |
… |
| % FEMALE |
64.7 |
69.8 |
65.2 |
50.0 |
0.003 |
| AGE AT AUDIT – mean (SD) |
53.1 (13.8) |
52.3 (13.6) |
54.6 (14.0) |
50.9 (13.5) |
0.046 |
| at diabetes diagnosis – mean (SD) |
42.9 (13.1) |
43.6 (12.8) |
43.9 (132.1) |
38.5 (13.2) |
0.002 |
| diabetes duration – mean (SD) |
9.3 (6.7) |
7.8 (5.9) |
9.9 (7.0) |
11.5 (7.2) |
0.000 |
| BODY MASS INDEX – mean (SD) |
34.0 (6.8) |
34.70 (6.4) |
34.33 (7.4) |
31.59 (5.7) |
0.001 |
| % SMOKER |
41.6 |
42.2 |
36.7 |
52.2 |
0.04 |
| BLOOD PRESSURE |
|
|
|
|
|
| sBP mm Hg – mean (SD) |
131.4 (16.8) |
128.7 (15.1) |
133.5 (17.4) |
132.7 (18.5) |
0.004 |
| dBP mm Hg – mean (SD) |
76.2 (10.7) |
75.9 (10.2) |
77.0 (10.5) |
75.11 (12.3) |
n/s |
| BLOOD TESTS |
|
|
|
|
|
| AIC % – mean (SD) |
8.28 (2.26) |
7.72 (1.92) |
8.34 (2.21) |
9.58 (2.64) |
0.000 |
| TC mM – mean (SD) |
4.51 (1.04) |
4.38 (0.93) |
4.49 (1.01) |
4.93 (1.24) |
0.000 |
| LDL mM – mean (SD) |
2.37 (1.82) |
2.33 (0.77) |
2.31 (0.81) |
2.65 (0.93) |
0.003 |
| HDL mM – mean (SD) |
1.22 (0.30) |
1.20 (0.29) |
1.20 (0.30) |
1.30 (0.33) |
0.017 |
| COMORBIDITIES |
|
|
|
|
|
| % eye disease |
11.5 |
7.4 |
13 |
18.1 |
0.015 |
| % neuropathy |
10.6 |
6.6 |
11.7 |
18.1 |
0.007 |
| MEDICATIONS |
|
|
|
|
|
| % Insulin |
28.5 |
19.4 |
33.2 |
39.4 |
0.000 |
| % RAAS agents | 74.6 | 67.4 | 75.7 | 90.4 | 0.000 |
*sBP-systolic blood pressure, dBP-diastolic blood pressure, A1C-glycosylated hemoglobin, TC-total cholesterol, LDL-LDL cholesterol, HDL-HDL cholesterol, RAAS agents- containing angiotensin converting enzyme inhibitors or angiotensin receptor blockers.
**Micro-albuminuria plus Macro-albuminuria. = CKD-alb.