TABLE 3.

Overview of absolute organ weights and organ weight/body weight ratios in control and LGR7 knockout mice^a

Organ and units	Data for males of genotype:			Data for females of genotype:
	+/+	+/−	−/−	+/+	+/−	−/−
Body wt (g)	30.3 ± 1.8	29.6 ± 1.2	30.2 ± 1.6	23.8 ± 1.2	25.5 ± 0.9	24.4 ± 1.3
Heart
mg	153 ± 10	156 ± 11	151 ± 7	126 ± 6	141 ± 8	122 ± 6
%	0.50 ± 0.01	0.52 ± 0.03	0.50 ± 0.01	0.53 ± 0.02	0.55 ± 0.03	0.50 ± 0.02
Spleen
mg	100 ± 6	109 ± 4	99 ± 11	106 ± 9	119 ± 4	94 ± 8
%	0.33 ± 0.02	0.37 ± 0.02	0.33 ± 0.02	0.45 ± 0.04	0.47 ± 0.01	0.38 ± 0.02
Thymus
mg	58.7 ± 3.3	66.5 ± 6.5	68.8 ± 4.4	69.1 ± 7.6	55.8 ± 10.3	71.2 ± 6
%	0.20 ± 0.01	0.23 ± 0.02	0.23 ± 0.02	0.29 ± 0.03	0.22 ± 0.03	0.29 ± 0.02
Liver
g	1.73 ± 0.09	1.55 ± 0.07	1.68 ± 0.09	1.21 ± 0.07	1.43 ± 0.05	1.23 ± 0.07
%	5.75 ± 0.27	5.26 ± 0.19	5.55 ± 0.06	5.11 ± 0.21	5.62 ± 0.12	5.05 ± 0.12
Kidneys
mg	409 ± 32	381 ± 28	439 ± 23	283 ± 23	311 ± 13b	314 ± 19
%	1.34 ± 0.04	1.28 ± 0.05	1.46 ± 0.04	1.18 ± 0.05	1.22 ± 0.02	1.29 ± 0.06
Adrenal glands
mg	9.9 ± 1.2	8.1 ± 0.8	8.2 ± 0.9	10.5 ± 1.3	11.4 ± 0.8	11.3 ± 0.6
%	0.034 ± 0.004	0.028 ± 0.003	0.028 ± 0.004	0.044 ± 0.005	0.045 ± 0.004	0.047 ± 0.004
Brain
mg	479 ± 9	475 ± 12	505 ± 9	497 ± 8	499 ± 8	496 ± 5
%	1.60 ± 0.09	1.61 ± 0.03	1.70 ± 0.09	2.11 ± 0.10	1.96 ± 0.06	2.06 ± 0.11
Testes
mg	205 ± 17	206 ± 21	117 ± 15c
%	0.68 ± 0.04	0.69 ± 0.05	0.39 ± 0.05d
Epididymides
mg	84.0 ± 6.2	79.0 ± 7.5	62.3 ± 4.3b
%	0.28 ± 0.02	0.27 ± 0.02	0.21 ± 0.02
Seminal vesicles
mg	326 ± 19 (5)	335 ± 32	280 ± 18
%	1.08 ± 0.08	1.12 ± 0.08	0.93 ± 0.04
Ovaries
mg				13.5 ± 0.9	13.1 ± 0.7	14.1 ± 0.9
%				0.057 ± 0.003	0.052 ± 0.003	0.059 ± 0.005
Uterus
mg				101 ± 12	104 ± 20	94 ± 14
%				0.43 ± 0.05	0.41 ± 0.08	0.38 ± 0.04

^aValues represent means ± standard errors of the means. Unless otherwise indicated in parentheses, the number of mice per group was six. Organ weight/body weight ratios are given as percents.

^bP value, <0.05.

^cP value, <0.01.

^dP value, <0.001.