. 2012 Jun 15;5:299. doi: 10.1186/1756-0500-5-299

Table 4.

Minimal inhibitory concentration (MIC) in μg/ml of antibiotics in the absence and presence sub-inhibitory concentrations ofAframomum citratumextract against some MDR bacteria

Bacterial strains	*Antibiotics and MIC in absence and presence ofAframomum citratumextract*
Bacterial strains		Ampicillin			Cefepime			Chloramphenicol			Ciprofloxacin			Cloxacillin
	Alone	MIC/2.5	MIC/5	Alone	MIC/2.5	MIC/5	Alone	MIC/2.5	MIC/5	Alone	MIC/2.5	MIC/5	Alone	MIC/2.5	MIC/5
AG100Atet	-	-	-	-	-	-	256	32 (8) ^S	64 (4) ^S	256	128 (2) ^S	256 (1) ^I	-	-	-
AG102	-	-	-	128	128 (1) ^I	128 (1) ^I	16	8 (2) ^S	8 (2) ^S	<2	<2	<2	-	-	-
CM64	-	256 (1)^I	-	-	64 (>4) ^S	-	nt	nt	nt	nt	nt	nt	-	-	-
KP63	-	32 (>8)^S	-	256	32 (8) ^S	256 (1) ^I	-	64 (>4) ^S	256 (>1)^S	64	64 (1) ^I	64 (1) ^I	-	256 (>1)^S	-
PA124	128	16 (8) ^S	64 (2) ^S	128	128 (1) ^I	256 (0.5) ^I	32	16 (2) ^S	16 (2) ^S	16	4 (4) ^S	16 (1) ^I	-	-	-
Bacterial strains	Erythromycin			Kanamycin			Norfloxacin			Streptomycin			Tetracyclin
Bacterial strains	Alone	MIC/2.5	MIC/5	Alone	MIC/2.5	MIC/5	Alone	MIC/2.5	MIC/5	Alone	MIC/2.5	MIC/5	Alone	MIC/2.5	MIC/5
AG100Atet	64	16 (4) ^S	32 (2) ^S	-	32 (>8)^S	256	128	16 (8) ^S	128 (1) ^I	<2	<2	<2	2	<2 (>1)^S	2 (1) ^I
AG102	32	16 (2) ^S	16 (2) ^S	<2	<2	<2	<2	<2	<2	-	128 (>2)^S	256 (>1)^S	<2	<2	<2
CM64	-	128 (>2)^S	256 (>1)^S	4	<2	<2	4	<2 (>2)^S	4 (1) ^I	32	4 (8) ^S	8 (4) ^S	nt	nt	nt
KP63	16	<1 (>16)^S	4 (4) ^S	32	16 (2) ^S	32 (1) ^I	-	128 (>2)^S	256 (>1)^S	<4	<4	<4	<2	<2	<2
PA124	128	64 (2) ^S	64 (2) ^S	128	16 (8) ^S	64 (2) ^S	64	8 (8) ^S	32 (2) ^S	nt	nt	nt	8	2 (4) ^S	2 (4) ^S

MIC/2.5: concentration of plant extract added equal to 204.8 μg/mL for AG100A_TET. KP63; and to 409.6 μg/mL for PA124. CM64. AG102.

MIC/5: concentration of plant extract added equal to 102. 4 μg/mL for AG100A_TET. KP63; and to 204.8 μg/mL for PA124. CM64. AG102.

(): Folds decreasing of MIC. S: synergy. I: indifference. nt: not tested; (−): MIC > 256.