TABLE 5.
Overexpression of STN1 but not TEN1 phenocopies loss of the NMD pathway
Genotype | Median PD | n | Median differencea | Lower limit | Upper limit |
---|---|---|---|---|---|
est2Δ PGAL1-STN1 | 53 | 6 | |||
est2Δ PGAL1-STN1 upf2Δ | 65 | 6 | 10 | −0.6 | 13.9 |
tlc1Δ YEP PGAL1-TEN1 | 62 | 11 | |||
tlc1Δ YEP PGAL1-TEN1 upf2Δ | 80 | 11 | 17* | 10 | 19 |
est2Δ PGAL1-STN1 + YEP-TEN1 | 64 | 10 | |||
est2Δ PGAL1-STN1 + YEP-TEN1 upf2Δ | 64 | 8 | −0.3 | −0.8 | 0.04 |
*, significant (P < 0.05) median difference (Hodges-Lehmann estimator) (45). n = number of independent isolates.