Table 3. Percentage neutralization of IgG₁s m43, m48, m14, m18, b12, 2F5 and 4E10 at 30 µg/ml against 30 HIV-1 primary isolates from different clades in TZM-bl and PBMC-p24 assays.

Virus	Clade	Tropism	TZM-bl assay									PBMC assay
			m9	m14	m18	m43	m48	b12	2F5	4E10	21.2	m9	m14	m18	m43	m48	b12	2F5	4E10	21.2
92UG_029	A	X4	99	56	30	0	0	95	97	91	99	34	0	0	0	0	95	31	9	42
93RW_024	A	Dual	18	0	0	0	0	0	93	75	85	85	0	0	0	0	nd	66	0	38
00KE_KER2008	A	Dual	85	0	0	0	0	0	85	84	89	0	18	9	0	0	0	42	31	43
99KE_KNH1135	A	R5	14	0	11	20	3	100	92	83	73	96	29	32	64	69	95	81	93	75
00KE_KSM 4030	A	R5	0	0	0	0	0	0	97	95	91	72	72	49	77	32	31	81	72	85
89BZ_167	B	X4	0	84	100	100	0	95	100	99	99	0	61	91	43	12	70	70	60	99
92FR_BXO8	B	R5	98	84	83	86	0	85	92	89	98	99	37	46	1	19	70	51	23	99
90US_873	B	R5	93	30	18	22	0	100	99	93	96	79	0	45	60	47	93	96	89	99
96TH_NP1538	B	R5	69	0	0	0	0	0	61	44	89	94	0	4	18	19	nd	84	39	85
91US_4	B	R5	84	0	0	0	6	58	72	73	95	99	68	48	49	46	45	94	81	99
89SM_145	C	R5	86	24	9	6	15	0	0	90	83	52	4	8	45	0	nd	0	53	30
01TZ_911	C	R5	60	10	0	1	4	5	0	90	90	82	0	4	58	0	nd	0	0	29
98US_MSC5016	C	R5	83	70	40	31	0	0	18	98	87	95	0	0	0	0	nd	0	0	0
94IN_20635-4	C	R5	99	51	5	0	0	99	0	96	95	90	43	51	54	39	99	8	73	95
00TZ_A125	C	R5	16	0	0	0	10	0	0	83	54	42	42	27	50	24	64	39	36	53
00UG_D26830M4	D	R5	0	12	0	8	0	4	59	62	98	96	0	33	3	35		66	0	82
93UG_065	D	X4	99	21	18	16	6	5	99	90	78	96	67	45	73	28	19	70	62	64
99UG_AO8483M1	D	R5	90	87	86	88	10	100	74	59	97	99	36	52	25	0	99	86	62	83
98UG_57128	D	R5	94	65	60	65	16	100	1	70	86	92	60	40	59	26	98	10	56	50
00KE_NKU3006	D	R5	71	17	0	8	4	67	93	87	49	95	25	55	0	0	nd	74	34	37
90TH_CM235	AE	R5	19	24	0	23	24	22	91	80	70	26	0	11	0	0	nd	64	8	53
90TH_CM240	AE	R5	95	21	29	30	33	20	90	90	87	20	0	0	18	0	nd	10	37	9
96TH_NI1149	AE	R5	14	10	23	14	16	12	3	91	66	87	28	71	72	52	nd	19	47	92
96TH_M02138	AE	X4	0	21	33	25	0	16	99	97	90	2	0	0	0	0	nd	23	0	51
90TH_CM244	AE	R5	0	24	27	17	37	9	95	89	85	nd	nd	nd	nd	nd	nd	nd	nd	nd
02CM_1970LE	AG	R5	10	15	18	12	8	16	99	98	85	93	18	35	14	19	nd	72	0	40
98US_MSC5007	AG	R5	91	9	13	15	0	5	74	83	78	87	23	28	52	32	40	93	74	81
02CM_ 0013BBY	AG	R5	58	9	16	24	5	6	0	90	73	94	51	42	45	66	67	70	66	72
02CM_0015BBY	AG	R5	25	45	20	9	7	33	95	94	79	68	0	0	12	0	nd	48	11	45
02CM_0014BBY	AG	R5	36	12	6	5	13	19	19	91	83	93	8	53	1	19	nd	13	26	71
Percentage of virus neutralized			57	23	13	13	0	33	70	97	97	76	21	21	34	10	63	55	41	66

HIV-1-infected patient serum (pool 21.2) was included as a control. Percentage neutralization of viral infection are color coded so that the darker the color, the more potent the neutralization: a white box indicated <50% neutralization, a light grey box indicates 50%< percentage neutralization <90%, and a dark grey box indicates percentage neutralization >90%. n.d., not done.