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. Author manuscript; available in PMC: 2012 Sep 10.
Published in final edited form as: Leuk Lymphoma. 2011 Sep 19;53(2):211–217. doi: 10.3109/10428194.2011.608451

Table II.

Adverse Events (grade 3-4) Attributable to CpG 7909 Therapy

Dose Level Dose (mg/kg) Number of Grade 3-4 AEs

IV Arm SQ Arm Cross-Over Arm

1 0.15 0 1a -
2 0.45 0 2b -
3 0.75 0 4c -
4 IV 1.05 (×1) - - 1d
SQ 0.45 (× 4-8)
a

Grade 4 neutropenia

b

One grade 3 cancer-related pain, one grade 3 SGPT (ALT)

c

Two grade 3 myalgia, one grade 3 fatigue, one grade 3 constitutional symptom

d

Grade 3 headache