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. Author manuscript; available in PMC: 2013 Sep 1.
Published in final edited form as: J Immunol. 2012 Jul 27;189(5):2563–2573. doi: 10.4049/jimmunol.1102762

Figure 6. Induction of AP-1 DNA binding activity by PGE2.

Figure 6

A, An ELISA-based (Trans-AM®) method was used to analyze DNA binding activities of AP-1 from differentiated THP-1 mϕ treated with PGE2 (10 µM) for 0–120 min. B–D, DNA binding activities of AP-1 family of proteins B, Fos (cFos, FosB), C, Jun (JunB, cJun, JunD) and D, Fra-1 in nuclear proteins extracts from cells treated with PGE2 (10 µM) for 60 min. Data are mean ± SD (n=3). *, p<0.05; ** p<0.01 compared to control.