Table 3.
Category | Antibiotic therapy not introducedn = 104(45.2%) | Antibiotic therapy introducedn = 126(54.8%) | Univariate Analyses | Multivariate Analyses | ||||
RR | 95% CI | p-value | RR | 95% CI | p-value | |||
RSV (+)* | 71 (48.6) | 75 (51.4) | 0.85 | 0.59-1.21 | 0.357 | - | - | |
Age > 6 months | 08 (20.5) | 31 (79.5) | 1.60 | 1.07-2.40 | 0.023 | 0.95 | 0.61-1.48 | 0.808 |
Male | 56 (43.4) | 73 (56.6) | 0.93 | 0.65-1.32 | 0.676 | - | - | |
Fever on admission | 56 (37.3) | 94 (62.7) | 1.57 | 1.05-2.34 | 0.028 | 0.93 | 0.60-1.44 | 0.745 |
Thoracic radiography with opacification | 18 (18.2) | 81 (81.8) | 2.41 | 1.65-3.52 | <0.001 | 1.48 | 0.94-2.32 | 0.091 |
ICU | 14 (35.9) | 25 (64.1) | 1.21 | 0.78-1.88 | 0.389 | - | - | |
MV | 02 (12.5) | 14 (87.5) | 1.67 | 0.96-2.91 | 0.070 | 1.30 | 0.74-2.28 | 0.370 |
AOM | 00 (00.0) | 12 (100) | 1.91 | 1.05-3.47 | 0.033 | 4.66 | 2.28-9.51 | <0.001 |
Pneumonia | 01 (1.1) | 94 (98.9) | 4.17 | 2.79-6.23 | <0.001 | 4.16 | 2.53-6.85 | <0.001 |
Leukocyte count*<9,0009-13,000>13,000 | 15 (31.3)15 (32.6)16 (29.1) | 33 (68.7)31 (67.4)39 (70.9) | 1.02 | 0.81-1.28 | 0.890 | - | - | |
Oximetry %mean (sd) | 91 (0.4) | 89 (0.4) | 0.96 | 0.92-1.01 | 0.101 | - | - |
VIRUS(+) = etiological diagnosis of infection with any respiratory virus; RSV(+) = etiological diagnosis of infection with respiratory syncytial virus; *Result unavailable at the moment of introduction of antibiotic therapy; ICU = intensive care unit; MV = mechanical ventilation; AOM = diagnosis of acute otitis media; RR = relative risk; #Number of cells/ml; ##Oximetry was analyzed as a continuous variable, whereas the other variables were categorized.