Table 1.

Effect of simvastatin and/or losartan on lipid profiles in mice sera

ApoE^-/- mice were fed with a high-fat high-cholesterol (HFHC) diet for 12 weeks with or without drug treatment. Effects of simvastatin and/or losartan on total cholesterol (T-CHO), triglyceride (TG), low density lipoprotein-cholesterol (LDL-C) and high density lipoprotein-cholesterol (HDL-C) in plasma of HFHC-fed apoE^-/- mice were measured. S: simvastatin, L: losartan, S+L: simvastatin plus losartan, apoE^-/-: apolipopretein E