Figure 1. Tonic activation of adult quiescent neural stem cells by GABA via α₅β₃γ₂ GABA_ARs.

a, Sample traces of whole-cell voltage-clamp recording from GFP⁺ RGLs with treatment of diazepam (1 μM), flumazenil (10 μM), midazolam (10 μM), ETMD (100 nM), or L-655708 (50 μM), followed by BMI (100 μM) to obtain baseline for normalizing tonic responses for each cell. b, Summary of normalized amplitude of tonic response. Values represent mean ± s.e.m. (n = 4–5 cells; all significantly different from the basal condition; P < 0.05; student t-test).