Table 4.

Experimental validation results for the 10 computational hits predicted as 5-HT_2B ligands as a result of QSAR-based mining of the WDI chemical screening library.

Compound ID	Chemical Stucture/Name	PubChem CID	PDSP ID	Predicted 5-HT2B Activity	Experimental Ki (nM)
1		43922	14809	Active	2,495
2		71028	14807	Active	491
3		114709	14806	Active	>10,000
4		3038495	14814	Active	33.1
5		3336	14821	Active	3,217
6		1715104	14815	Active	151.4
7		4140	27769	Active	0.8
8		195658	14805	Active	1,617
9		9909648	13513	Active	69.6
10		15940170	13505	Active	69