Fig. 3.
Interleukin protein expression plotted as a ratio to the internal control protein (IC) in the cerebral cortex of ovine fetuses at 122–127 days of gestation exposed the ischemia and reperfusion insult.
Panel A shows: Representative Western immunoblots of IL-1β protein expression are shown for each study group. IL-1β protein expression in cerebral cortex of the non-ischemic control ovine fetuses (open bar, n=6), ischemic ovine fetuses exposed to 48 hours (gray bar, n=5), or 72 hours of reperfusion (closed bar, n=6); [ANOVA, main effect for treatment, F (2, 14) = 29.4, P < 0.001]. Values are m±SD, * P<0.05 versus ischemic control ovine fetuses.
Panel B shows: Representative Western immunoblots of IL-6 protein expression are shown for each study group. IL-6 protein expression in cerebral cortex of the non-ischemic control ovine fetuses (n=6), ischemic ovine fetuses exposed to 48 hours (n=6) or 72 hours of reperfusion [ANOVA, main effect for treatment, F (2,14) = 0.60, P = 0.56. Symbol legends as for A.
